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Brian Shifrin at Fenway Park
Understanding ALS

What is Amyotrophic Lateral Sclerosis?

Also known as Lou Gehrig's disease

ALS is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord. It breaks the connection between the brain and muscles, and together, we're fighting to change that.

30,000+Americans currently living with ALS
5,000+New cases diagnosed each year in the U.S.
2-5 YearsAverage life expectancy after diagnosis
90%Of cases occur without family history
What Changes

How ALS Affects the Body

When motor neurons begin to die, the body gradually loses the ability to move, speak, eat, and eventually breathe. Families often need practical help just as quickly as they need clear information.

Motor Neurons

ALS attacks the nerve cells responsible for controlling voluntary muscle movement, disrupting signals from brain to body.

Signal Disruption

As neurons degenerate, the electrical signals that tell muscles to move become weaker and eventually stop entirely.

Muscle Weakness

Without nerve stimulation, muscles weaken and atrophy. Early signs can include difficulty gripping, tripping, or dropping things.

Progressive Spread

ALS typically starts in one area, such as a hand, foot, or tongue, and gradually spreads to other muscle groups throughout the body.

Speech & Swallowing

Many people with ALS experience slurred speech and difficulty swallowing as the muscles of the mouth and throat weaken.

Breathing Difficulty

As respiratory muscles weaken, breathing support becomes necessary. This is one of the most critical challenges for those living with ALS.

SHIFSTRONG family on the water
For Families

A diagnosis changes the whole household.

SHIFSTRONG exists because ALS is never just medical. It affects routines, equipment needs, caregivers, children, finances, and the emotional weight of everyday life. We help families find support and connection before isolation has a chance to take over.

Voices in the Fight Against ALS

Behind every diagnosis is a story, a fight, and a community. SHIFSTRONG believes shared experiences help the next generation of ALS patients and families navigate this journey.